Annemarie C. Brescia, MD

Methotrexate inhibits BMP4 and abrogates the hypertrophic chondrocyte phenotype of synovial fibroblasts in juvenile idiopathic arthritis; Pediatric Rheumatology; (2024).

Adalimumab Effectively Decreases Inflammation Downstream of TNFα Signaling in Synoviocytes from Extended Oligoarticular Juvenile Idiopathic Arthritis; Rheumatology and Therapy; (2023).

CCL24, CXCL9 and CXCL10 are increased in synovial fluid in patients with juvenile idiopathic arthritis requiring advanced treatment; Rheumatology (United Kingdom); (2023).

Single-cell analysis reveals heterogeneity of juvenile idiopathic arthritis fibroblast-like synoviocytes with implications for disease subtype; Arthritis Research and Therapy; (2022).

An Atypical Case of Scurvy in an Adolescent With Sacroiliitis; Clinical Pediatrics; (2022).

The culture microenvironment of juvenile idiopathic arthritis synovial fibroblasts is favorable for endochondral bone formation through BMP4 and repressed by chondrocytes; Pediatric Rheumatology; (2021).

Distinct interferon signatures and cytokine patterns define additional systemic autoinflammatory diseases; Journal of Clinical Investigation; (2020).

Juvenile idiopathic arthritis fibroblast-like synoviocytes influence chondrocytes to alter BMP antagonist expression demonstrating an interaction between the two prominent cell types involved in endochondral bone formation; Pediatric Rheumatology; (2020).

Juvenile Idiopathic Arthritis Fibroblast-like Synoviocytes, through BMP signaling, play a central role in joint growth disturbances; Research Square; (2020).

Prior to extension, transcriptomes of fibroblast-like synoviocytes from extended and polyarticular juvenile idiopathic arthritis are indistinguishable; Pediatric Rheumatology; (2018).

Unilateral Periorbital Swelling in Two Previously Healthy Females; Global Pediatric Health; (2017).

Secretion of pro-inflammatory cytokines and chemokines and loss of regulatory signals by fibroblast-like synoviocytes in juvenile idiopathic arthritis; Proteomics - Clinical Applications; (2017).

The role of transforming growth factor β signaling in fibroblast-like synoviocytes from patients with oligoarticular juvenile idiopathic arthritis: dysregulation of transforming growth factor β signaling, including overexpression of bone morphogenetic protein 4, may lead to a chondrocyte phenotype and may contribute to bony hypertrophy.; Arthritis & rheumatology (Hoboken, N.J.); (2014).

Lyme chondritis presenting as painless ear erythema; Pediatrics; (2013).

Prognostic Impact of Atypical Presentation in Pediatric Systemic Lupus Erythematosus: Results from a Multicenter Study; Journal of Pediatrics; (2010).

Prolonged synovitis in pediatric lyme arthritis cannot be predicted by clinical or laboratory parameters; Clinical Rheumatology; (2009).

Focus on Subspecialties, Importance of Immunizations:; AAP News; (2009).

Predicting duration of beneficial effect of joint injection among children with chronic arthritis by measuring biomarkers concentration in synovial fluid at the time of injection; Clinical and Experimental Rheumatology; (2008).

Steady improvement of prothrombin levels after cyclophosphamide therapy in pediatric lupus anticoagulant hypoprothrombinemia syndrome (LAHPS); Clinical Rheumatology; (2007).

Joint Swelling; Pediatrics on Call; (2006).

Process for the Preparation of Bis(Amidocarboxylic Acids); Unknown Source; (1995).

Process for the Prepartion of Bis(Amidocarboxylic Acid); Unknown Source; (1995).

One-pot synthesis of cyclic amidinium tetrafluoroborates and hexafluorophosphates; the simplest models of N5, N10-methenyl-tetrahydrofolate coenzyme; Tetrahedron Letters; (1991).