Anilkumar Gopalakrishnapillai

Down syndrome and leukemia: An insight into the disease biology and current treatment options.; Blood reviews; (2023).

Tetraspanins set the stage for bone marrow microenvironment-induced chemoprotection in hematologic malignancies.; Blood advances; (2023).

Bone Marrow Microenvironment-Induced Chemoprotection in <i>KMT2A</i> Rearranged Pediatric AML Is Overcome by Azacitidine–Panobinostat Combination; Cancers; (2023).

Efficacy of Flotetuzumab in Combination with Cytarabine in Patient-Derived Xenograft Models of Pediatric Acute Myeloid Leukemia; Journal of Clinical Medicine; (2022).

Mesothelin: An Immunotherapeutic Target beyond Solid Tumors; Cancers; (2022).

Imetelstat Induces Leukemia Stem Cell Death in Pediatric Acute Myeloid Leukemia Patient-Derived Xenografts; Journal of Clinical Medicine; (2022).

Modeling Down Syndrome Myeloid Leukemia by Sequential Introduction of <i>GATA1</i> and <i>STAG2</i> Mutations in Induced Pluripotent Stem Cells with Trisomy 21; Cells; (2022).

A 3-D hydrogel based system for hematopoietic differentiation and its use in modeling down syndrome associated transient myeloproliferative disorder; Biomaterials Science; (2021).

Mesothelin is a novel cell surface disease marker and potential therapeutic target in Acute Myellid Leukemia; Blood advances; (2021).

Immunotherapeutic Targeting of Mesothelin Positive Pediatric AML Using Bispecific T Cell Engaging Antibodies; Cancers; (2021).

Harnessing the Power of Induced Pluripotent Stem Cells and Gene Editing Technology: Therapeutic Implications in Hematological Malignancies; Cells; (2021).

The Menin-MLL1 interaction is a molecular dependency in NUP98-rearranged AML; Blood; (2021).

Error-corrected sequencing strategies enable comprehensive detection of leukemic mutations relevant for diagnosis and minimal residual disease monitoring.; BMC medical genomics; (2020).

CD81 knockout promotes chemosensitivity and disrupts in vivo homing and engraftment in acute lymphoblastic leukemia.; Blood advances; (2020).

Modeling Transient Abnormal Myelopoiesis Using Induced Pluripotent Stem Cells and CRISPR/Cas9 Technology.; Molecular therapy. Methods & clinical development; (2020).

Understanding the Mechanisms by Which Epigenetic Modifiers Avert Therapy Resistance in Cancer.; Frontiers in oncology; (2020).

Strong concordance between RNA structural and single nucleotide variants identified via next generation sequencing techniques in primary pediatric leukemia and patient-derived xenograft samples.; Genomics & informatics; (2020).

The extracellular matrix: A key player in the pathogenesis of hematologic malignancies.; Blood reviews; (2020).

Epigenetic drug combination overcomes osteoblast-induced chemoprotection in pediatric acute lymphoid leukemia.; Leukemia research; (2017).

Epigenetic drug combination induces remission in mouse xenograft models of pediatric acute myeloid leukemia.; Leukemia research; (2017).

CRISPR/Cas9-Directed Reassignment of the GATA1 Initiation Codon in K562 Cells to Recapitulate AML in Down Syndrome.; Molecular therapy. Nucleic acids; (2017).

Eviction from the sanctuary: Development of targeted therapy against cell adhesion molecules in acute lymphoblastic leukemia.; Seminars in oncology; (2017).

Knockdown of sodium-calcium exchanger 1 induces epithelial-to-mesenchymal transition in kidney epithelial cells.; The Journal of biological chemistry; (2017).

Generation of Pediatric Leukemia Xenograft Models in NSG-B2m Mice: Comparison with NOD/SCID Mice.; Frontiers in oncology; (2016).

Disruption of Annexin II /p11 Interaction Suppresses Leukemia Cell Binding, Homing and Engraftment, and Sensitizes the Leukemia Cells to Chemotherapy.; PloS one; (2015).

Ion dependence of Na-K-ATPase-mediated epithelial cell adhesion and migration.; American journal of physiology. Cell physiology; (2015).

Sodium-calcium exchanger 1 regulates epithelial cell migration via calcium-dependent extracellular signal-regulated kinase signaling.; The Journal of biological chemistry; (2015).

Metformin suppresses pediatric acute myeloid leukemia cell viability and clonogenicity.; Cancer & metabolism; (2014).

Ellagic acid stimulates glucose transport in adipocytes and muscles through AMPK mediated pathway; Journal of diabetes and metabolism; (2012).

A Comprehensive Curated Reaction Map of Leptin Signaling Pathway; Jornal of Proteomics and bioinformatics; (2011).

Elucidation of the glucose transport pathway in glucose transporter 4 via steered molecular dynamics simulations.; PloS one; (2011).

Association analysis of common variants in FOXO3 with type 2 diabetes in a South Indian Dravidian population.; Gene; (2011).

Vanillin induces adipocyte differentiation in 3T3-L1 cells by activating extracellular signal regulated kinase 42/44.; Life sciences; (2011).

Molecular dynamics simulation studies of GLUT4: substrate-free and substrate-induced dynamics and ATP-mediated glucose transport inhibition.; PloS one; (2010).

A case-control analysis of common variants in GIP with type 2 diabetes and related biochemical parameters in a South Indian population.; BMC medical genetics; (2010).

Case-control analysis of SNPs in GLUT4, RBP4 and STRA6: association of SNPs in STRA6 with type 2 diabetes in a South Indian population.; PloS one; (2010).

Homology modeling of GLUT4, an insulin regulated facilitated glucose transporter and docking studies with ATP and its inhibitors.; Journal of biomolecular structure & dynamics; (2009).

Gallic acid induces GLUT4 translocation and glucose uptake activity in 3T3-L1 cells.; FEBS letters; (2009).

Kaempferitrin inhibits GLUT4 translocation and glucose uptake in 3T3-L1 adipocytes.; Biochemical and biophysical research communications; (2009).

Preferential association of prostate cancer cells expressing prostate specific membrane antigen to bone marrow matrix.; International journal of oncology; (2007).

Functional characterization of AAA family FtsH protease of Mycobacterium tuberculosis.; FEMS microbiology letters; (2006).

Association of prostate-specific membrane antigen with caveolin-1 and its caveolae-dependent internalization in microvascular endothelial cells: implications for targeting to tumor vasculature.; Microvascular research; (2006).

Is prostate-specific membrane antigen a multifunctional protein?; American journal of physiology. Cell physiology; (2005).

N-glycosylation and microtubule integrity are involved in apical targeting of prostate-specific membrane antigen: implications for immunotherapy.; Molecular cancer therapeutics; (2005).

Genomic organization and in vivo characterization of proteolytic activity of FtsH of Mycobacterium smegmatis SN2.; Microbiology (Reading, England); (2004).

Novel role for Na,K-ATPase in phosphatidylinositol 3-kinase signaling and suppression of cell motility.; Molecular biology of the cell; (2004).

A novel cytoplasmic tail MXXXL motif mediates the internalization of prostate-specific membrane antigen.; Molecular biology of the cell; (2003).

Prostate-specific membrane antigen association with filamin A modulates its internalization and NAALADase activity.; Cancer research; (2003).

Bacterial cell division protein FtsZ is a specific substrate for the AAA family protease FtsH.; Microbiology (Reading, England); (2001).

Cloning and expression of the gene coding for FtsH protease from Mycobacterium tuberculosis H37Rv.; Gene; (1998).

Newly synthesised mRNA as a probe for identification of wound responsive genes from potatoes.; Indian journal of biochemistry & biophysics; (1995).