Andrew W. Walter, MD

Hematology/Oncology

Primary Office

Nemours Children's Hospital, Delaware Nemours Children's Hospital, Delaware 1600 Rockland Road Wilmington, DE 19803 Appointment: (800) 416-4441

Get to Know Me

I grew up in the New York City area. As a child, I was something of a science geek. I enjoyed applying what I learned to real life situations. As a pediatric cancer specialist, I always focus on helping kids with cancer and brain tumors enjoy the best possible quality of life.

Why I Treat Children

I have tremendous respect for the children in my care. Although most are very sick, they handle adversity amazingly well. They don’t complain and just want to be done with treatment so they can go on with their lives.

How I Try to Make A Difference

I try to make a difference through hope and healing. The fact that Nemours is so active in cancer research means we have access to experimental treatment options that offer real hope for a cure. Just as important, we do everything we can to make a terrible process less terrible by alleviating any suffering.

Education & Training

Fellowship

  • Pediatric Hematology/Oncology - University of Michigan, 1992

Internship

  • Pediatrics - The Children's Hospital of Philadelphia, 1987

Residency

  • Pediatrics - The Children's Hospital of Philadelphia, 1989

Medical/Dental School

  • M.D. - University of Rochester, 1986
  • M.S. - University of Rochester, 1986

Board Certifications

  • American Board of Pediatrics/Pediatric Hematology-Oncology

Awards & Recognition

  • 2014 Best Doctors in America
  • 2013 Best Doctors in America
  • 2011 Best Doctors in America

Insurance Accepted

  • Aetna Better Health PA Kids HMO
  • Aetna HMO
  • Aetna PPO/POS/EPO
  • Amerihealth Caritas Delaware
  • Carefirst MD Community Health Plan Mcaid
  • Cigna Lifesource Transplant
  • Cigna/Great West HMO EPO POS
  • Cigna/Great West PPO
  • Delaware First Health
  • Delaware Medicaid/Diamond State
  • Delaware Medicare
  • Devon Health Services
  • Fidelis Care NJ Medicaid HMO
  • First Health/Affordable PPO
  • Geisinger Health Plan Commercial
  • Health Partners Medicaid/Kidz Partner HMO
  • Highmark Blue Cross Blue Shield of Delaware
  • Highmark Medicaid Health Options
  • Horizon Blue Cross Blue Shield of New Jersey
  • Independance Blue Cross/Amerihealth/Keystone Health Plan
  • Insurance Administrators of America
  • INTEGRA Administrative Group (ClaimsBridge)
  • Keystone First Medicaid HMO
  • Lifetrac Transplant
  • Maryland Medicaid
  • Multiplan PPO
  • New Jersey Medicaid
  • Pennsylvania Medicaid
  • Plan Vista/NPPN PPO
  • Preferred Healthcare PPO
  • Private Health Care Systems (PHCS)
  • Qualcare HMO/POS/PPO
  • Star Healthcare Network
  • Three Rivers Provider Network
  • Tricare/Humana Military Health Services/CHAMPVA
  • United Healthcare of the Mid-Atlantic
  • UPMC MCAID/CHIP PA DE
  • Wellpoint Maryland Medcaid

  • Brain Tumors
  • Cancer Care
  • Solid Tumors

Research Activities

In my research I helped describe and measure the learning problems that brain tumor patients can have following radiation therapy.

Medical Interests

  • Brain stem gliomas
  • Brain tumors
  • Chemotherapy
  • Gorlin syndrome
  • Low grade gliomas
  • Malignant gliomas
  • Medulloblastoma ependymoma

  • Clinical Characteristics and Outcomes of Central Nervous System Tumors Harboring NTRK Gene Fusions; Clinical Cancer Research; (2025).

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  • The Rise of WNT-Activated Medulloblastoma?; Unknown Source; (2024).

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  • Mechanical properties of pediatric low-grade gliomas in children with and without neurofibromatosis type 1; Neuroradiology; (2024).

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  • WNT-activated, MYC-amplified medulloblastoma displaying intratumoural heterogeneity; Neuropathology and Applied Neurobiology; (2024).

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  • Clinical Outcomes and Complications of Pituitary Blastoma; Journal of Clinical Endocrinology and Metabolism; (2021).

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  • Clinical Outcomes and Patient-Matched Molecular Composition of Relapsed Medulloblastoma; Journal of Clinical Oncology; (2021).

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  • Clinical phenotypes and prognostic features of embryonal tumours with multi-layered rosettes: a Rare Brain Tumor Registry study; The Lancet Child and Adolescent Health; (2021).

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  • Surveillance for subsequent neoplasms of the CNS for childhood, adolescent, and young adult cancer survivors: a systematic review and recommendations from the International Late Effects of Childhood Cancer Guideline Harmonization Group; The Lancet Oncology; (2021).

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  • Clinical phenotypes and prognostic features of ETMRs (Embryonal Tumor with Multi-layered Rosettes) a new CNS tumor entity: A Rare Brain Tumor Registry study; medRxiv; (2020).

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  • Excellent outcome of young children with nodular desmoplastic medulloblastoma treated on "head Start" III: A multi-institutional, prospective clinical trial; Neuro-Oncology; (2020).

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  • Larotrectinib imaging response in low-grade glioma; Pediatric Blood and Cancer; (2020).

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  • Pleuropulmonary blastoma-like peritoneal sarcoma: a newly described malignancy associated with biallelic DICER1 pathogenic variation; Modern Pathology; (2020).

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  • Bone marrow transplant and pediatric multiple myeloma; Pediatric Blood and Cancer; (2019).

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  • Medulloblastoma and secondary acute myeloid leukemia in a patient with Turner syndrome; Pediatric Blood and Cancer; (2019).

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  • Constitutional LZTR1 mutation presenting with a unilateral vestibular schwannoma in a teenager; Clinical Genetics; (2017).

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  • Posterior reversible encephalopathy syndrome and cerebral sinus thrombosis in a case of pediatric B-Cell ALL; Journal of Pediatric Hematology/Oncology; (2017).

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  • Divergent clonal selection dominates medulloblastoma at recurrence; Nature; (2016).

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  • Hypothalamic glioma in a patient with Sturge-Weber syndrome; Journal of Pediatric Hematology/Oncology; (2016).

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  • Topical amphotericin B in combination with standard therapy for severe necrotizing skin and soft-tissue mucormycosis in an infant with bilineal leukemia: Case report and review; Journal of Pediatric Hematology/Oncology; (2014).

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  • Constitutional mismatch repair deficiency presenting in childhood as three simultaneous malignancies; Pediatric Blood and Cancer; (2013).

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  • Recurrence patterns across medulloblastoma subgroups: An integrated clinical and molecular analysis; The Lancet Oncology; (2013).

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  • Rituximab as potential therapy for paraneoplastic cerebellar degeneration in pediatric Hodgkin disease; Pediatric Blood and Cancer; (2012).

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  • Favorable outcome with conservative treatment for children with low grade brainstem tumors; Pediatric Blood and Cancer; (2012).

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  • Infantile choriocarcinoma in a neonate with massive liver involvement cured with chemotherapy and liver transplant; Journal of Pediatric Hematology/Oncology; (2011).

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  • Ehrlichia-induced hemophagocytic lymphohistiocytosis in two children; Pediatric Blood and Cancer; (2011).

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  • Granulocyte colony stimulating factor in neonatal alloimmune neutropenia: A possible association with induced thrombocytopenia; Pediatric Blood and Cancer; (2010).

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  • Pancytopenia in hospitalized children: A five-year review; Journal of Pediatric Hematology/Oncology; (2010).

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  • Regarding "Intrathecal vincristine: 3 fatal cases and a review of the literature".; Journal of pediatric hematology/oncology : official journal of the American Society of Pediatric Hematology/Oncology; (2010).

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  • Regarding "intrathecal vincristine: 3 fatal cases and a review of the literature"; Journal of Pediatric Hematology/Oncology; (2010).

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  • Natural progression of an unresected supratentorial ependymoma; Pediatric Neurosurgery; (2007).

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  • Central nervous system atypical teratoid/rhabdoid tumor: Results of therapy in children enrolled in a registry; Journal of Clinical Oncology; (2004).

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  • Brain tumors in children; Current Oncology Reports; (2004).

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  • Persistent questions about the treatment of severe aplastic anemia in children as illustrated by five cases; Hematology; (2003).

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  • Severe aplastic anemia associated with hepatitis and complicated by pulmonary aspergillosis: response to immune suppression and antifungal therapy.; Delaware medical journal; (2002).

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  • Tamoxifen and carboplatin for children with low-grade gliomas: A pilot study at st. jude children's research hospital; American Journal of Pediatric Hematology/Oncology; (2000).

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  • Long-term results with radiation therapy for pediatric desmoid tumors; International Journal of Radiation Oncology Biology Physics; (2000).

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  • Silent lacunar lesions detected by magnetic resonance imaging of children with brain tumors: A late sequela of therapy; Journal of Clinical Oncology; (2000).

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  • CNS involvement in children with newly diagnosed non-Hodgkin's lymphoma; Journal of Clinical Oncology; (2000).

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  • Changes in body mass index and prevalence of overweight in survivors of childhood acute lymphoblastic leukemia: Role of cranial irradiation; Medical and Pediatric Oncology; (2000).

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  • Comparison of lumbar and shunt cerebrospinal fluid specimens for cytologic detection of leptomeningeal disease in pediatric patients with brain tumors; Journal of Clinical Oncology; (1999).

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  • Comparison of CSF cytology and spinal magnetic resonance imaging in the detection of leptomeningeal disease in pediatric medulloblastoma or primitive neuroectodermal tumor; Journal of Clinical Oncology; (1999).

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  • Direct translation of a protracted irinotecan schedule from a xenograft model to a phase I trial in children; Journal of Clinical Oncology; (1999).

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  • High incidence of secondary brain tumours after radiotherapy and antimetabolites; Lancet; (1999).

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  • Survival and neurodevelopmental outcome of young children with medulloblastoma at St Jude Children's Research Hospital; Journal of Clinical Oncology; (1999).

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  • Cyclophosphamide for the treatment of progressive low-grade astrocytoma: A Pediatric Oncology Group Phase II study; Journal of Pediatric Hematology/Oncology; (1999).

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  • A pilot study of vincristine, ifosfamide, and doxorubicin in the treatment of pediatric non-rhabdomyosarcoma soft tissue sarcomas; Medical and Pediatric Oncology; (1998).

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  • Bithalamic involvement predicts poor outcome among children with thalamic glial tumors; Pediatric Neurosurgery; (1998).

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  • Secondary brain tumors in children treated for acute lymphoblastic leukemia at St Jude Children's Research Hospital; Journal of Clinical Oncology; (1998).

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  • Carboplatin and etoposide with hyperfractionated radiotherapy in children with newly diagnosed diffuse pontine gliomas: A phase I/II study; Medical and Pediatric Oncology; (1998).

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  • Letter to the editor: Errors involving pediatric patients receiving chemotherapy: A literature review [2] (multiple letters); Medical and Pediatric Oncology; (1997).

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  • Complications of the nevoid basal cell carcinoma syndrome: A case report; Journal of Pediatric Hematology/Oncology; (1997).

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  • Low-grade astrocytoma: A decade of experience at St. Jude Children's Research Hospital; Journal of Clinical Oncology; (1997).

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  • Patterns of failure in children with medulloblastoma: Effects of preirradiation chemotherapy; International Journal of Radiation Oncology Biology Physics; (1997).

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  • Post-irradiation malignant mesothelioma [6]; Cancer; (1997).

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  • Supratentorial malignant gliomas in childhood: A single institution perspective; Cancer; (1997).

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  • DNA index of glial tumors in children: Correlation with tumor grade and prognosis; Cancer; (1996).

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  • Gorlin syndrome associated with midline nasal dermoid cyst; Journal of Medical Genetics; (1996).

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  • Medulloblastoma with brain stem involvement: The impact of gross total resection on outcome; Pediatric Neurosurgery; (1996).

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  • Low-grade astrocytoma with neuraxis dissemination at diagnosis; Journal of Neurosurgery; (1995).

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  • Neurourologic consequences of accidental intrathecal vincristine: A case report; Medical and Pediatric Oncology; (1995).

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  • Preirradiation chemotherapy with carboplatin and etoposide in newly diagnosed embryonal pediatric CNS tumors; Journal of Clinical Oncology; (1995).

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  • Stereotactic injection of herpes simplex thymidine kinase vector producer cells (PA317-G1Tk1SvNa.7) and intravenous ganciclovir for the treatment of progressive or recurrent primary supratentorial pediatric malignant brain tumors; Human Gene Therapy; (1995).

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  • Final height after treatment for childhood acute lymphoblastic leukemia: Comparison of no cranial irradiation with 1800 and 2400 centigrays of cranial irradiation; The Journal of Pediatrics; (1993).

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  • Human hematopoietic stem cell adherence to cytokines and matrix molecules; Journal of Clinical Investigation; (1992).

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