Pasquale Casale, MD

Urology

Primary Office

Nemours Children's Hospital, Delaware Nemours Children's Hospital, Delaware 1600 Rockland Road Wilmington, DE 19803 Appointment: (800) 416-4441

Other Offices

Get to Know Me

Pasquale Casale, MD, MHA is a devoted husband and father who dedicated his career to helping children through the field of pediatric urology. He has pioneered many minimally invasive surgeries that were never before performed on children, to allow them to heal faster. He chose pediatric urology because it is multifaceted and deals with important personal issues such as sexuality and continence, as well as painful conditions and malignancies. 

Why I Treat Children

I chose pediatric urology because it is very important to take care of children. We lost our son, and we were devastated. His journey made me realize how precious life is. Children are truly impactful in the world. They play a special component in our lives that sometimes we take for granted. One of the most rewarding parts of being a pediatric urologist is helping children get through issues that sometimes are difficult to openly discuss, as they can be very intimate problems. Some are very social problems that can stop children from normal activities like sleepovers and dating. The problems can pose future issues with relationships and gender identity, so being able to make a difference for those children in such a very personal arena is simply amazing. Therefore, making a difference for them whether it’s surgical or just through counseling or just by holding someone’s hand to tell them that everything is going to be OK is priceless.

What I'm Passionate About

The overall health, well-being and safety of my patients drives me. Decreasing poor outcomes and getting kids back to the business of being kids as soon as possible is paramount to me. Time is precious, so the faster we can have children recover, the more time they will have to develop themselves. I have dedicated my academic career to minimally invasive surgery. It is one of the most exciting things that is happening in pediatric urology. Because of smaller instrumentation and robotic technology, we can do procedures never thought possible to be done in a minimal fashion in kids easily. We can ensure that their healing process is faster. We can also ensure that they get back to their normal activities sooner than with conventional open surgery. We can do this type of surgery with robotics through what we call laparoscopic access, which are incisions the size of a grain of rice. Patients typically go home the next day and I have them going back to full activities within two weeks.  

How I Try to Make A Difference

I made a simple “ABC Rule” of how I care for patients. Availability — my patients always have access to me not only through my office but also through email as well as my cell. I encourage them to reach out any time day or night if they have questions or concerns. I'm there for them. Bonding — Every child I care for becomes part of who I am. My relationship with the patients and families is very important to me. Understanding their perspective and needs will help me give them the safest and most effective, personal care they require to get better. Compassion — One of the most vulnerable times in one's life is when they are seeking medical advice. We, or someone we love, have all experienced that feeling. It can be a scary and helpless time. I believe listening, caring and diligence is the trifecta of patient safety and good care. I am honored to be given the privilege of caring for them and help them get to a healthier life. 

Education & Training

Fellowship

  • Pediatric Urology - University of Washington School of Medicine, 2004

Residency

  • General Surgery - Beth Israel Medical Center, 1998
  • Urology - Jefferson Medical College - Residency, 2002

Medical/Dental School

  • M.D. - Albert Einstein College of Medicine, 1996

Board Certifications

  • American Board of Urology
  • American Board of Urology/Pediatric Urology

Awards & Recognition

  • 2023Super Doctor, SuperDoctors.com
  • 2009–2023Patient’s Choice Award
  • 2005–2023Top Doctors, Castle Connolly
  • 2005–2023Honor Roll, Healthgrades
  • 2005–2023Patients’ Top Choice Award, U.S. News & World Report
  • 2016–2020Top Doctors, New York Metro Area (digital guide)
  • 2014–2019Top Doctors, New York Magazine
  • 2012–2018Samberg Scholar, N.Y. Presbyterian Hospital
  • 2015Top Doctors, New York Metro Area (book series, 18th edition)
  • 2014Top Doctors, New York Metro Area (book series, 17th edition)
  • 2004Fellow Achievement Award, Society of Laparoendoscopic Surgeons
  • 2003Fellow Achievement Award, Society of Laparoendoscopic Surgeons
  • 2002Gerald P. Murphy Scholar Award for Prostate Cancer
  • 2002The Pfizer Scholars in Urology Award
  • 1996Distinction in Research, Reconstructive Surgery

  • Congenital Hydronephrosis
  • Cryptorchidism
  • Hypospadias
  • Neurogenic Bladder
  • Urinary Stone Disease
  • Vesicoureteral Reflux
  • Voiding Dysfunction

Research Activities

  • Minimally Invasive Surgery
  • Robotic Surgery
  • Endoscopy
  • Laparoscopy
  • Simulation and Training
  • Surgical Device Development Patent Acquisition

Medical Interests

  • Minimally Invasive Surgery
  • Robotic Surgery
  • Endoscopy
  • Laparoscopy
  • Urologic Oncology
  • Renal Transplantation
  • Trauma and Reconstructive Surgery
  • Hydronephrosis
  • Urinary Stone Disease
  • Obstructive Uropathy
  • Vesicoureteral Reflux
  • Fetal Urology

  • Robotic Pediatric Renal Surgery; Robotic Urologic Surgery: Third Edition; (2022).

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  • Author Correction: The copy number variation landscape of congenital anomalies of the kidney and urinary tract (Nature Genetics, (2019), 51, 1, (117-127), 10.1038/s41588-018-0281-y); Nature Genetics; (2019).

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  • The copy number variation landscape of congenital anomalies of the kidney and urinary tract; Nature Genetics; (2019).

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  • Ureteral reimplantation; Pediatric Robotic Surgery: Technical and Management Aspects; (2017).

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  • Innovation in Robotics and Pediatric Urology: Robotic Ureteroureterostomy for Duplex Systems with Ureteral Ectopia; Journal of Endourology; (2016).

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  • Intra- and inter-observer variability of functional MR urography (fMRU) assessment in children; Pediatric Radiology; (2016).

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  • Is outpatient robotic pyeloplasty feasible?; Journal of Robotic Surgery; (2016).

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  • Editorial Comment for Silay et al.; Journal of Endourology; (2015).

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  • The Robotic-Assisted Laparoscopic Pyeloplasty: Gateway to Advanced Reconstruction; Urologic Clinics of North America; (2015).

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  • Is peri-operative urethral catheter drainage enough? The case for stentless pediatric robotic pyeloplasty; Journal of Pediatric Urology; (2015).

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  • Laser ablation in the management of obstructive uropathy in neonates; Journal of Endourology; (2015).

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  • How to decide which infant can have robotic surgery? Just do the math; Journal of Pediatric Urology; (2015).

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  • Serum Cystatin C as a Novel Marker to Differentiate Pseudoazotemia in the Setting of Intraperitoneal Urine Extravasation; Urology; (2015).

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  • Learning curves, costs, and practical considerations; Pediatric Endourology Techniques; (2014).

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  • Noninvasive ureterocele puncture using pulsed focused ultrasound: An in vitro study; Journal of Endourology; (2014).

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  • Pediatric surgeons and anesthesiologists expand the dialogue on the neurotoxicity question, rationale for early and delayed surgeries, and practice changes while awaiting definitive evidence; Journal of Neurosurgical Anesthesiology; (2014).

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  • Robotic surgery in pediatric urology; Current Urology Reports; (2014).

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  • Learning curve of robotic assisted pyeloplasty for pediatric urology fellows; Journal of Urology; (2013).

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  • Morbidity and efficacy of ureteroscopic stone treatment in patients with neurogenic bladder; Journal of Urology; (2013).

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  • Robotic surgery of the kidney and ureter in pediatric patients; Current Urology Reports; (2013).

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  • Elective procedures and anesthesia in children: Pediatric surgeons enter the dialogue on neurotoxicity questions, surgical options, and parental concerns; Journal of Neurosurgical Anesthesiology; (2012).

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  • Robotic-assisted laparoscopic surgery in pediatric urology: An update,Pediyatrik ürolojide robot yardımlı laparoskopik cerrahi: Bir güncelleme; Turk Uroloji Dergisi; (2012).

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  • How does acute urolithiasis present after renal denervation?; Journal of Endourology; (2012).

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  • Minimally invasive survey in infants: Pro; Journal of Urology; (2012).

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  • Pediatric laparoscopic and robot-assisted laparoscopic surgery: Technical considerations; Journal of Endourology; (2012).

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  • Pediatric urologic robotic surgery – purs; Robotic Urologic Surgery, Second Edition; (2012).

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  • Prospective long-term analysis of nerve-sparing extravesical robotic-assisted laparoscopic ureteral reimplantation; Urology; (2012).

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  • Flexible ureteroscopy in children with von Willebrand disease; Journal of Endourology; (2012).

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  • Robot-assisted bladder diverticulectomy in the pediatric population; Journal of Endourology; (2012).

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  • Robotic-Assisted Extravesical Ureteral Reimplantation; Pediatric Robotic and Reconstructive Urology: A Comprehensive Guide; (2012).

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  • Endoscopic management and the role of double stenting for primary obstructive megaureters; Journal of Urology; (2012).

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  • Unilateral hypercalciuria: A stealth culprit in recurrent ipsilateral urolithiasis in children; Journal of Urology; (2012).

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  • What Pediatricians Need to Know about Urology; Pediatric Clinics of North America; (2012).

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  • Multiple metachronous fibroepithelial polyps in children; Journal of Urology; (2011).

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  • Undescended testis; Fundamentals of Pediatric Surgery; (2011).

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  • Vesicoureteral reflux; Fundamentals of Pediatric Surgery; (2011).

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  • Robotic hypospadias surgery: A new evolution; Journal of Robotic Surgery; (2010).

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  • Editorial Comment; Journal of Urology; (2010).

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  • Editorial comment; Journal of Urology; (2010).

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  • Laparoscopic and robotic approach to genitourinary anomalies in children; Urologic Clinics of North America; (2010).

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  • Page kidney in an adolescent with recent onset of hypertension and slightly decreased renal function: Question; Pediatric Nephrology; (2010).

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  • Prospective analysis of completely stentless robot-assisted pyeloplasty in children; Journal of Robotic Surgery; (2010).

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  • A review of pediatric laparoscopic pyeloplasty; UroToday International Journal; (2009).

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  • Robotic correction of Östling folds as a rare cause of ureteropelvic junction obstruction in children; Journal of Robotic Surgery; (2009).

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  • Editorial Comment; Urology; (2009).

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  • Port-site complications after pediatric urologic robotic surgery; Journal of Robotic Surgery; (2009).

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  • Reply by the Authors; Urology; (2009).

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  • Robotic pediatric urology; Current Urology Reports; (2009).

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  • Robotic pyeloplasty in the pediatric population; Current Urology Reports; (2009).

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  • Robotic pyeloplasty in the pediatric population; Current Opinion in Urology; (2009).

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  • Robotic ureteroureterostomy in children with a duplex collecting system; Journal of Robotic Surgery; (2009).

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  • Robotic-assisted laparoscopic surgery in pediatric urology: An update; Scandinavian Journal of Surgery; (2009).

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  • Initial validation of a virtual-reality robotic simulator; Journal of Robotic Surgery; (2008).

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  • Editorial Comment; Journal of Urology; (2008).

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  • Follow-up for laparoscopic renal denervation and nephropexy for autosomal dominant polycystic kidney disease-related pain in pediatrics; Journal of Endourology; (2008).

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  • Robotic Ureterocalicostomy in the Pediatric Population; Journal of Urology; (2008).

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  • Renal vein varix and UPJ obstruction: A case report and techniques for robotic management; Journal of Robotic Surgery; (2008).

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  • Pediatric Flexible Ureteroscopic Lithotripsy: The Children's Hospital of Philadelphia Experience; Journal of Urology; (2008).

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  • Nerve Sparing Robotic Extravesical Ureteral Reimplantation; Journal of Urology; (2008).

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  • Robotic pediatric urology; Expert Review of Medical Devices; (2008).

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  • VR robotic surgery: Randomized blinded study of the dV-Trainer robotic simulator; Studies in Health Technology and Informatics; (2008).

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  • Testicular Compartment Syndrome: A New Approach to Conceptualizing and Managing Testicular Torsion; Urology; (2008).

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  • Congenital anomalies; Penn Clinical Manual of Urology; (2007).

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  • Editorial Comment; Journal of Urology; (2007).

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  • Laparoscopic orchiopexy; BJU International; (2007).

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  • Robotic pediatric urology; Minerva Urologica e Nefrologica; (2007).

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  • Laparoscopic and robotic complex upper-tract reconstruction in children with a duplex collecting system; Journal of Endourology; (2007).

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  • Low-dose intrathecal morphine for postoperative analgesia in children; Anesthesia and Analgesia; (2007).

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  • Robot Assisted Pyeloplasty in the Infant-Lessons Learned; Journal of Urology; (2006).

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  • Can a Complete Primary Repair Approach be Applied to Cloacal Exstrophy?; Journal of Urology; (2006).

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  • Initial Experience With Laparoscopic Transvesical Ureteral Reimplantation at the Children's Hospital of Philadelphia; Journal of Urology; (2006).

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  • Laparoscopic Renal Denervation and Nephropexy for Autosomal Dominant Polycystic Kidney Disease Related Pain in Adolescents; Journal of Urology; (2006).

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  • Laparoscopic pyeloplasty in the infant younger than 6 months - Is it technically possible?; Journal of Urology; (2006).

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  • Lower pole pelvi-ureteric junction obstruction in duplicated collecting systems; BJU International; (2006).

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  • Modified Bladder Neck Reconstruction in Patients With Incontinence After Staged Exstrophy/Epispadias Closures; Journal of Urology; (2006).

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  • Transperitoneal laparoscopic pyeloplasty for pelvic kidneys with ureteropelvic junction obstruction in children: technique and preliminary outcomes.; JSLS : Journal of the Society of Laparoendoscopic Surgeons / Society of Laparoendoscopic Surgeons; (2006).

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  • Bilateral dismembered laparoscopic pediatric pyeloplasty via a transperitoneal 4-port approach; Journal of Urology; (2005).

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  • Recurrent urinary tract infection in the post-transplant reflux nephropathy patient: Is reflux in the native ureter the culprit?; Pediatric Transplantation; (2005).

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  • Symptomatic refluxing distal ureteral stumps after nephroureterectomy and heminephroureterectomy. What should we do?; Journal of Urology; (2005).

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  • A novel approach to the laparoscopic antegrade continence enema procedure: Intracorporeal and extracorporeal techniques; Journal of Urology; (2004).

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  • Cloacal exstrophy variants. Can blighted conjoined twinning play a role?; Journal of Urology; (2004).

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  • Comparison of dismembered and nondismembered laparoscopic pyeloplasty in the pediatric patient; Journal of Endourology; (2004).

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  • Intracorporeal laparoscopic appendicovesicostomy: A case report of a novel approach; Journal of Urology; (2004).

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  • The pediatric caliceal diverticulum: Diagnosis and laparoscopic management; Journal of Endourology; (2004).

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  • The ureter as a pedicle for construction of a ureteral urethra: The double tunnel; Journal of Urology; (2004).

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  • Transperitoneal laparoscopic pyelolithotomy after failed percutaneous access in the pediatric patient; Journal of Urology; (2004).

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  • Female urology; Clinics Atlas of Office Procedures; (2002).

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