Robert Akins, PhD
Center Director/Principal Research Scientist- Cardiovascular Disease
- Cerebral Palsy
- Dna Methylation
- Epigenomics
- Machine Learning
- Materials Science, Polymers, Implants
- Neuroscience
- Noncoding Rna
- Perinatal Onset Disease
- Regenerative Medicine
- Stem Cells
- Surgery
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Factors Associated with Antihypertensive Therapy Prescription in Youth Delaware Medicaid Recipients with Primary Hypertension Diagnosis; American Journal of Hypertension; (2024).
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The circular RNA circNFIX regulates MEF2C expression in muscle satellite cells in spastic cerebral palsy; Journal of Biological Chemistry; (2024).
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Abstract P635: Poverty, Sodium Intake and Abnormal Blood Pressure Among Youth 13 to 18 Years of Age; Circulation; (2023).
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SOCIO-DEMOGRAPHIC-ECONOMIC STATUS IS A SIGNIFICANT PREDICTOR OF COVID-19 RELATED HOSPITALIZATIONS IN CHILDREN AND YOUNG ADULTS: POPULATION LEVEL ANALYSIS BASED ON US NATIONAL COVID COHORT COLLABORATIVE (N3C) DATA; Journal of the American College of Cardiology; (2023).
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MICRONUTRIENT INTAKE AND HYPERTENSION AMONG ADOLESCENTS, NHANES 2007-2018; Journal of Hypertension; (2023).
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Association of Area Deprivation With Primary Hypertension Diagnosis Among Youth Medicaid Recipients in Delaware.; JAMA network open; (2023).
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Collagenase treatment decreases muscle stiffness in cerebral palsy: A preclinical ex vivo biomechanical analysis of hip adductor muscle fiber bundles.; Developmental medicine and child neurology; (2023).
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Epigenetic Biomarkers for Spastic Cerebral Palsy; Unknown Source; (2023).
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Launching IDeA state early career clinician-scientists with mentored just-in-time grant-writing support; Journal of Clinical and Translational Science; (2023).
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Abstract 17653: Neighborhood Deprivation and Cardiovascular Health in US Adolescents, National Health and Nutrition Examination Survey 2007-2018; Circulation; (2023).
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Abstract 17079: Relationship Between Neighborhood Level Deprivation and Cardiovascular Health Status Among 122,177 Adolescents, Analysis of PEDSnet Data; Circulation; (2023).
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Abstract 17035: Relationship Between Neighborhood Level Deprivation and Blood Pressure Among 122,177 Adolescents, Analysis of PEDSnet Data; Circulation; (2023).
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Exploring the Multifaceted Biologically Relevant Roles of circRNAs: From Regulation, Translation to Biomarkers; Cells; (2023).
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DNA Methylation Analysis Reveals Distinct Patterns in Satellite Cell–Derived Myogenic Progenitor Cells of Subjects with Spastic Cerebral Palsy; Journal of Personalized Medicine; (2022).
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Machine learning in epigenetic diseases; Medical Epigenetics; (2021).
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Machine learning in epigenetic diseases; Medical Epigenetics; (2021).
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Substrate stiffness directs the phenotype and polarization state of cord blood derived macrophages; Acta Biomaterialia; (2021).
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Resistance to Neuromuscular Blockade by Rocuronium in Surgical Patients with Spastic Cerebral Palsy; Journal of Personalized Medicine; (2021).
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Transcriptional analysis of muscle tissue and isolated satellite cells in spastic cerebral palsy; Developmental Medicine & Child Neurology; (2021).
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An Emerging Role for Epigenetics in Cerebral Palsy; Journal of Personalized Medicine; (2021).
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Scientific Posters; Developmental Medicine & Child Neurology; (2020).
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Neointimal Hyperplasia after Carotid Transection and Anastomosis Surgery is Associated with Degradation of Decorin and Platelet Derived Growth Factor Signaling.; JVS-vascular science; (2020).
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Regulation of neovasculogenesis in co-cultures of aortic adventitial fibroblasts and microvascular endothelial cells by cell-cell interactions and TGF-β/ALK5 signaling.; PloS one; (2020).
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Identification of epigenetic signatures indicating cerebral palsy; USPTO; (2020).
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Method for protecting skeletonized blood vessels; USPTO; (2020).
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Human Adventitial Fibroblast Phenotype Depends on the Progression of Changes in Substrate Stiffness.; Advanced healthcare materials; (2020).
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Neuromuscular Junction Changes in Spastic Cerebral Palsy; Cerebral Palsy: Second Edition; (2020).
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Biomarker Blood Tests for Cerebral Palsy; Cerebral Palsy: Second Edition; (2020).
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Biomarker Blood Tests for Cerebral Palsy; Cerebral Palsy; (2020).
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Scientific Posters; Developmental Medicine & Child Neurology; (2019).
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Neuromuscular Junction Changes in Spastic Cerebral Palsy; Cerebral Palsy; (2019).
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Spatial Patterning of Molecular Cues and Vascular Cells in Fully Integrated Hydrogel Channels via Interfacial Bioorthogonal Cross-Linking.; ACS applied materials & interfaces; (2019).
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Epigenetic machine learning: utilizing DNA methylation patterns to predict spastic cerebral palsy; BMC Bioinformatics; (2018).
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Motor unit diversity during elbow flexion; International IEEE/EMBS Conference on Neural Engineering, NER; (2017).
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Aortic adventitial fibroblast sensitivity to mitogen activated protein kinase inhibitors depends on substrate stiffness.; Biomaterials; (2017).
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Reduced arterial elasticity due to surgical skeletonization is ameliorated by abluminal PEG hydrogel.; Bioengineering & translational medicine; (2017).
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Attenuation of Maladaptive Responses in Aortic Adventitial Fibroblasts through Stimuli-Triggered siRNA Release from Lipid-Polymer Nanocomplexes.; Advanced biosystems; (2017).
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Resilin-PEG hybrid hydrogels yield degradable elastomeric scaffolds with heterogeneous microstructure; Biomacromolecules; (2016).
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Fetal Rat Gubernaculum Mesenchymal Cells Adopt Myogenic and Myofibroblast-Like Phenotypes; Journal of Urology; (2016).
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Polygenic inheritance of cryptorchidism susceptibility in the LE/orl rat; Molecular Human Reproduction; (2015).
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Phenotype specific association of the TGFBR3 locus with nonsyndromic cryptorchidism; Journal of Urology; (2015).
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Decreasing matrix modulus of PEG hydrogels induces a vascular phenotype in human cord blood stem cells; Biomaterials; (2015).
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Integrated wall stress: A new methodological approach to assess ventricular workload and myocardial contractile reserve; Journal of Translational Medicine; (2013).
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Neuromotor synapses in Escobar syndrome; American Journal of Medical Genetics, Part A; (2013).
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Disruption of Basal Lamina Components in Neuromotor Synapses of Children with Spastic Quadriplegic Cerebral Palsy; PLoS ONE; (2013).
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322; Critical Care Medicine; (2013).
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Electrospinning Fundamentals and Applications; Biomaterials Science; (2013).
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Reduced expression of androgen receptor and myosin heavy chain mRNA in cremaster muscle of boys with nonsyndromic cryptorchidism; Journal of Urology; (2012).
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In situ crosslinkable heparin-containing poly(ethylene glycol) hydrogels for sustained anticoagulant release; Journal of Biomedical Materials Research - Part A; (2012).
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Differential effects of substrate modulus on human vascular endothelial, smooth muscle, and fibroblastic cells; Journal of Biomedical Materials Research - Part A; (2012).
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Development of a force-driven distractor for distraction osteogenesis; Journal of Medical Devices, Transactions of the ASME; (2011).
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Continuous Force Measurement in Limb Lengthening; J Bioengineer & Biomedical Sci; (2011).
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Using distraction forces to drive an autodistractor during limb lengthening; Medical Engineering and Physics; (2011).
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Erratum: Production of heparin-containing hydrogels for modulating cell responses (Acta Biomaterialia 5 (2009) (865-875)); Acta Biomaterialia; (2010).
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Three-dimensional culture alters primary cardiac cell phenotype; Tissue Engineering - Part A; (2010).
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Identification of neuromuscular junctions by correlative confocal and transmission electron microscopy; Journal of Neuroscience Methods; (2010).
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Force feedback in limb lengthening.; Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Conference; (2010).
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Force feedback in limb lengthening; 2010 Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC'10; (2010).
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Optimizing limb lengthening using an autodistractor and force measurement; 2008 Proceedings of the 9th Biennial Conference on Engineering Systems Design and Analysis; (2009).
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Production of heparin-containing hydrogels for modulating cell responses; Acta Biomaterialia; (2009).
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Half-logistic time constants as inotropic and lusitropic indices for four sequential phases of isometric tension curves in isolated rabbit and mouse papillary muscles; International Heart Journal; (2009).
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C histomorphology of neuromuscular junction in Duchenne muscular dystrophy; Paediatric Anaesthesia; (2008).
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Altered expression of muscle- and cytoskeleton-related genes in a rat strain with inherited cryptorchidism; Journal of Andrology; (2008).
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Culture on electrospun polyurethane scaffolds decreases atrial natriuretic peptide expression by cardiomyocytes in vitro; Biomaterials; (2008).
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Characterization of electrospun poly(N-isopropyl acrylamide) fibers; Polymer; (2008).
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Half-logistic time constant: A more reliable lusitropic index than monoexponential time constant regardless of temperature in canine left ventricle; Canadian Journal of Physiology and Pharmacology; (2008).
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Characterization of intracellular Ca<sup>2+</sup> transient by the hybrid logistic function in aequorin-injected rabbit and mouse papillary muscles; Journal of Physiological Sciences; (2007).
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Gene expression profile of bioreactor-cultured cardiac cells: Activation of morphogenetic pathways for tissue engineering; DNA and Cell Biology; (2007).
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Growth and development in a heliox incubator environment: A long-term safety study; Neonatology; (2007).
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Growth and development in a heliox incubator environment: a long-term safety study.; Neonatology; (2007).
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Dysmorphic neuromuscular junctions associated with motor ability in cerebral palsy; Muscle and Nerve; (2005).
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Surgery and anesthesia for children who have cerebral palsy; Anesthesiology Clinics of North America; (2005).
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Exogenous metalloporphyrins alter the organization and function of cultured neonatal rat heart cells via modulation of heme oxygenase activity; Journal of Cellular Physiology; (2004).
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Tissue Engineering a Heart: Critical Issues; Functional Tissue Engineering; (2003).
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Identification of Nucleic Acid Binding Proteins Using Nondenaturing Sodium Decyl Sulfate Polyacrylamide Gel Electrophoresis (SDecS-PAGE); Protein Protocols Handbook, The; (2002).
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Cetyltrimethylammonium Bromide Discontinuous Gel Electrophoresis of Proteins: M<sub>r</sub> -Based Separation of Proteins with Retained Native Activity; Protein Protocols Handbook, The; (2002).
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Can tissue engineering mend broken hearts?; Circulation Research; (2002).
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Neuromuscular junctions in cerebral palsy: Presence of extrajunctional acetylcholine receptors; Anesthesiology; (2002).
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Cardiac Tissue; Methods of Tissue Engineering; (2002).
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Neuromuscular Junctions in Cerebral Palsy; Anesthesiology; (2002).
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Room 220-222, 10/16/2000 9: 00 AM - 10: 30 AM (PD) Neuromuscular Junction in Cerebral Palsy. Presence of Extrajunctional Acetylcholine Receptors; Anesthesiology; (2000).
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Isolated pancreatic amylase deficiency: Probable error in maturation; Journal of Pediatrics; (2000).
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Isolated pancreatic amylase deficiency: Probable error in maturation; Journal of Pediatrics; (2000).
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Cardiac organogenesis in vitro: reestablishment of three-dimensional tissue architecture by dissociated neonatal rat ventricular cells.; Tissue engineering; (1999).
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Cardiac organogenesis in vitro: Reestablishment of three-dimensional tissue architecture by dissociated neonatal rat ventricular cells; Tissue Engineering; (1999).
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Influence of calcium on proliferation and phenotype alteration of cardiomyocyte in vitro; Journal of Cellular Physiology; (1998).
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Neonatal rat heart cells cultured in simulated microgravity; In Vitro Cellular and Developmental Biology - Animal; (1997).
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Cetyltrimethylammonium Bromide Discontinuous Gel Electrophoresis of Proteins; The Protein Protocols Handbook; (1996).
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Atrial natriuretic peptide accelerates proliferation of chick embryonic cardiomyocytes in vitro; Differentiation; (1996).
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Ultrafast protein determinations using microwave enhancement; Molecular Biotechnology; (1995).
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Corrigendum; Molecular Biotechnology; (1995).
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Acetonitrile is better than ethanol as a dehydrating agent for cells prepared for SEM; Proceedings - Annual Meeting, Microscopy Society of America; (1994).
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Seperation of proteins using cetyltrimethylammonium bromide discontinuous gel electrophoresis; Molecular Biotechnology; (1994).
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Transepithelial calcium transport in the chick chorioallantoic membrane. I. Isolation and characterization of chorionic ectoderm cells.; Journal of cell science; (1993).
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Transepithelial calcium transport in the chick chorioallantoic membrane. II. Compartmentalization of calcium during uptake.; Journal of cell science; (1993).
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Transepithelial calcium transport in the chick chorioallantoic membrane II. Compartmentalization of calcium during uptake; Journal of Cell Science; (1993).
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Transepithelial calcium transport in the chick chorioallantoic membrane I. Isolation and characterization of chorionic ectoderm cells; Journal of Cell Science; (1993).
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Measurement of protein in 20 seconds using a microwave BCA assay; BioTechniques; (1992).
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Cetyltrimethylammonium bromide discontinuous gel electrophoresis: M<sub>r</sub>-based separation of proteins with retention of enzymatic activity; Analytical Biochemistry; (1992).
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Alterations in cellular calcium handling as a result of systemic calcium deficiency in the developing chick embryo: II. Ventricular myocytes; Journal of Cellular Physiology; (1992).
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In vitro study of placental trophoblast calcium uptake using JEG-3 human choriocarcinoma cells; Journal of Cell Science; (1991).
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Experimental studies on cultured, shell-less fowl embryos: calcium transport, skeletal development, and cardio-vascular functions; Egg Incubation; (1991).
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Bisphosphonate action: Alendronate localization in rat bone and effects on osteoclast ultrastructure; Journal of Clinical Investigation; (1991).
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Cryptorchidism in the orl rat is associated with muscle patterning defects in the fetal gubernaculum and altered hormonal signaling; Unknown Source; (0000).