Long-Term Outcomes After the Multisystem Inflammatory Syndrome in Children: MUSIC

Clinical Trial

Offered by: Nemours Children's
Location: Delaware Valley

Trial Name

Long-Term Outcomes After the Multisystem Inflammatory Syndrome in Children: MUSIC

What is the trial about?

To learn more about a condition called multisystem inflammatory syndrome in children (MIS-C) and the long-term health of children with MIS-C. MIS-C appears to be a late complication of COVID-19. While it is normal for the immune system to fight off an infection, children with MIS-C seem to have their immune systems turned on too strongly. This can affect many organ systems, including the heart. When children are diagnosed with MIS-C, they may have decreased heart function (meaning how the heart squeezes), enlargement of the coronary arteries (the blood vessels that bring oxygenated blood to the heart) and heart rhythm problems. However, we do not know the long-term effects of MIS-C on the heart or other organ systems. We are conducting this study to understand the short and longer-term effects of MIS-C on the heart and other organ systems in a large group of participants across North America.

Who can participate?

Patients with multisystem inflammatory syndrome in children (MIS-C).

What is involved?

A member of the research team will collect health information from your medical record.

If your doctor has not ordered certain tests as part of your clinical care, such as an echo, ECG or MRI, we may ask you for permission to do it for research. Participation in any testing done only for research will be optional.